Characterization of the Role of AMP-Activated Protein Kinase in the Regulation of Glucose-Activated Gene Expression Using Constitutively Active and Dominant Negative Forms of the Kinase

In the liver, glucose induces the expression of a number of genes involved in glucose and lipid metabolism, e.g., those encoding L-type pyruvate kinase and fatty acid synthase. Recent evidence has indicated a role for the AMP-activated protein kinase (AMPK) in the inhibition of glucose-activated gen...

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Detalhes bibliográficos
Main Authors: Woods, Angela, Azzout-Marniche, Dalila, Foretz, Marc, Stein, Silvie C., Lemarchand, Patricia, Ferré, Pascal, Foufelle, Fabienne, Carling, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86183/
https://ncbi.nlm.nih.gov/pubmed/10958668
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