Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

NF-κB is activated by various stimuli including inflammatory cytokines and stresses. A key step in the activation of NF-κB is the phosphorylation of its inhibitors, IκBs, by an IκB kinase (IKK) complex. Recently, two closely related kinases, designated IKKα and IKKβ, have been identified to be the c...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Nakano, Hiroyasu, Shindo, Masahisa, Sakon, Sachiko, Nishinaka, Shigeyuki, Mihara, Motoyuki, Yagita, Hideo, Okumura, Ko
التنسيق: Artigo
اللغة:Inglês
منشور في: The National Academy of Sciences 1998
الموضوعات:
Biological Sciences
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC19871/
https://ncbi.nlm.nih.gov/pubmed/9520401
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