Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

NF-κB is activated by various stimuli including inflammatory cytokines and stresses. A key step in the activation of NF-κB is the phosphorylation of its inhibitors, IκBs, by an IκB kinase (IKK) complex. Recently, two closely related kinases, designated IKKα and IKKβ, have been identified to be the c...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Nakano, Hiroyasu, Shindo, Masahisa, Sakon, Sachiko, Nishinaka, Shigeyuki, Mihara, Motoyuki, Yagita, Hideo, Okumura, Ko
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1998
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19871/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520401/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3537
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