Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly

The retinoic acid inducible gene-I (RIG-I)-like family of receptors is positioned at the front line of our innate cellular defence system. RIG-I detects and binds to foreign duplex RNA in the cytoplasm of both immune and non-immune cells, and initiates the induction of type I interferons and pro-inf...

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Detalhes bibliográficos
Main Authors: Beckham, Simone A., Brouwer, Jason, Roth, Anna, Wang, Die, Sadler, Anthony J., John, Matthias, Jahn-Hofmann, Kerstin, Williams, Bryan R. G., Wilce, Jacqueline A., Wilce, Matthew C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597671/
https://ncbi.nlm.nih.gov/pubmed/23325848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1477
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