RIG-I and dsRNA-Induced IFNβ Activation

Except for viruses that initiate RNA synthesis with a protein primer (e.g., picornaviruses), most RNA viruses initiate RNA synthesis with an NTP, and at least some of their viral (ppp)RNAs remain unblocked during the infection. Consistent with this, most viruses require RIG-I to mount an innate immu...

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Bibliographic Details
Main Authors: Hausmann, Stéphane, Marq, Jean-Baptiste, Tapparel, Caroline, Kolakofsky, Daniel, Garcin, Dominique
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607022/
https://ncbi.nlm.nih.gov/pubmed/19115016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003965
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