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RIG-I and dsRNA-Induced IFNβ Activation

Except for viruses that initiate RNA synthesis with a protein primer (e.g., picornaviruses), most RNA viruses initiate RNA synthesis with an NTP, and at least some of their viral (ppp)RNAs remain unblocked during the infection. Consistent with this, most viruses require RIG-I to mount an innate immu...

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Detalhes bibliográficos
Main Authors: Hausmann, Stéphane, Marq, Jean-Baptiste, Tapparel, Caroline, Kolakofsky, Daniel, Garcin, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607022/
https://ncbi.nlm.nih.gov/pubmed/19115016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003965
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