Activation of the Beta Interferon Promoter by Unnatural Sendai Virus Infection Requires RIG-I and Is Inhibited by Viral C Proteins

As infection with wild-type (wt) Sendai virus (SeV) normally activates beta interferon (IFN-β) very poorly, two unnatural SeV infections were used to study virus-induced IFN-β activation in mouse embryonic fibroblasts: (i) SeV-DI-H4, which is composed mostly of small, copyback defective interfering...

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Bibliographic Details
Main Authors: Strähle, Laura, Marq, Jean-Baptiste, Brini, Albert, Hausmann, Stéphane, Kolakofsky, Daniel, Garcin, Dominique
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169027/
https://ncbi.nlm.nih.gov/pubmed/17804509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01300-07
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