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Unpaired 5′ ppp-Nucleotides, as Found in Arenavirus Double-stranded RNA Panhandles, Are Not Recognized by RIG-I

Arenavirus and bunyavirus RNA genomes are unusual in that they are found in circular nucleocapsids, presumably due to the annealing of their complementary terminal sequences. Moreover, arenavirus genome synthesis initiates with GTP at position +2 of the template rather than at the precise 3′ end (po...

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Detalhes bibliográficos
Main Authors: Marq, Jean-Baptiste, Kolakofsky, Daniel, Garcin, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881745/
https://ncbi.nlm.nih.gov/pubmed/20400512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.089425
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