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Unpaired 5′ ppp-Nucleotides, as Found in Arenavirus Double-stranded RNA Panhandles, Are Not Recognized by RIG-I

Arenavirus and bunyavirus RNA genomes are unusual in that they are found in circular nucleocapsids, presumably due to the annealing of their complementary terminal sequences. Moreover, arenavirus genome synthesis initiates with GTP at position +2 of the template rather than at the precise 3′ end (po...

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Dettagli Bibliografici
Autori principali: Marq, Jean-Baptiste, Kolakofsky, Daniel, Garcin, Dominique
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881745/
https://ncbi.nlm.nih.gov/pubmed/20400512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.089425
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