Porcine deltacoronavirus nucleocapsid protein antagonizes IFN-β production by impairing dsRNA and PACT binding to RIG-I

Porcine deltacoronavirus (PDCoV) is an emerging swine enteropathogenic coronavirus that causes watery diarrhea, vomiting and mortality in newborn piglets. Previous studies have suggested that PDCoV infection antagonizes RIG-I-like receptor (RLR)-mediated IFN-β production to evade host innate immune...

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Bibliografiske detaljer
Udgivet i:Virus Genes
Main Authors: Chen, Jun, Fang, Puxian, Wang, Mohan, Peng, Qi, Ren, Jie, Wang, Dang, Peng, Guiqing, Fang, Liurong, Xiao, Shaobo, Ding, Zhen
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2019
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Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088841/
https://ncbi.nlm.nih.gov/pubmed/31129785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11262-019-01673-z
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