BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs

Inflammation is critical for host defense, but without appropriate control, it can cause chronic disease or even provoke fatal responses. Here we identify a mechanism that limits the inflammatory response. Probing the responses of macrophages to the key sensory Toll-like receptors, we identify that...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Sadler, Anthony J., Rossello, Fernando J., Yu, Liang, Deane, James A., Yuan, Xiangliang, Wang, Die, Irving, Aaron T., Kaparakis-Liaskos, Maria, Gantier, Michael P., Ying, Hangjie, Yim, Howard C. H., Hartland, Elizabeth L., Notini, Amanda J., de Boer, Suzan, White, Stefan J., Mansell, Ashley, Liu, Jun-Ping, Watkins, D. Neil, Gerondakis, Steve, Williams, Bryan R. G., Xu, Dakang
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321291/
https://ncbi.nlm.nih.gov/pubmed/25605927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409728112
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