Cell type-specific effects of Rb deletion in the murine retina

Certain cells of the human retina are extremely sensitive to loss of function of the retinoblastoma tumor suppressor gene RB. Retinoblastomas develop early in life and at high frequency in individuals heterozygous for a germ-line RB mutation, and sporadic retinoblastomas invariably have somatic muta...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: MacPherson, David, Sage, Julien, Kim, Teresa, Ho, Dennis, McLaughlin, Margaret E., Jacks, Tyler
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC478190/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15231717/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1203304
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