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Cell type-specific effects of Rb deletion in the murine retina
Certain cells of the human retina are extremely sensitive to loss of function of the retinoblastoma tumor suppressor gene RB. Retinoblastomas develop early in life and at high frequency in individuals heterozygous for a germ-line RB mutation, and sporadic retinoblastomas invariably have somatic muta...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC478190/ https://ncbi.nlm.nih.gov/pubmed/15231717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1203304 |
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