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Cell type-specific effects of Rb deletion in the murine retina

Certain cells of the human retina are extremely sensitive to loss of function of the retinoblastoma tumor suppressor gene RB. Retinoblastomas develop early in life and at high frequency in individuals heterozygous for a germ-line RB mutation, and sporadic retinoblastomas invariably have somatic muta...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: MacPherson, David, Sage, Julien, Kim, Teresa, Ho, Dennis, McLaughlin, Margaret E., Jacks, Tyler
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC478190/
https://ncbi.nlm.nih.gov/pubmed/15231717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1203304
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