Recapitulation of the Effects of the Human Papillomavirus Type 16 E7 Oncogene on Mouse Epithelium by Somatic Rb Deletion and Detection of pRb-Independent Effects of E7 In Vivo

Although the human papillomavirus (HPV) E7 oncogene is known to contribute to the development of human cervical cancer, the mechanisms of its carcinogenesis are poorly understood. The first identified and most recognized function of E7 is its binding to and inactivation of the retinoblastoma tumor s...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Balsitis, Scott J., Sage, Julien, Duensing, Stefan, Münger, Karl, Jacks, Tyler, Lambert, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309665/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645521/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.24.9094-9103.2003
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