A higher-order entity formed by the flexible assembly of RAP1 with TRF2

Telomere integrity is essential to maintain genome stability, and telomeric dysfunctions are associated with cancer and aging pathologies. In human, the shelterin complex binds TTAGGG DNA repeats and provides capping to chromosome ends. Within shelterin, RAP1 is recruited through its interaction wit...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Gaullier, Guillaume, Miron, Simona, Pisano, Sabrina, Buisson, Rémi, Le Bihan, Yann-Vaï, Tellier-Lebègue, Carine, Messaoud, Wala, Roblin, Pierre, Guimarães, Beatriz G., Thai, Robert, Giraud-Panis, Marie-Josèphe, Gilson, Eric, Le Du, Marie-Hélène
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770236/
https://ncbi.nlm.nih.gov/pubmed/26748096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1531
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