Загрузка...
The basic N-terminal domain of TRF2 limits recombination endonuclease action at human telomeres
The stability of mammalian telomeres depends upon TRF2, which prevents inappropriate repair and checkpoint activation. By using a plasmid integration assay in yeasts carrying humanized telomeres, we demonstrated that TRF2 possesses the intrinsic property to both stimulate initial homologous recombin...
Сохранить в:
| Главные авторы: | , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2014
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4128890/ https://ncbi.nlm.nih.gov/pubmed/25483196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29422 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|