Á lódáil...
TRF2/RAP1 and DNA–PK mediate a double protection against joining at telomeric ends
DNA-dependent protein kinase (DNA-PK) is a double-strand breaks repair complex, the subunits of which (KU and DNA-PKcs) are paradoxically present at mammalian telomeres. Telomere fusion has been reported in cells lacking these proteins, raising two questions: how is DNA–PK prevented from initiating...
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| Main Authors: | , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group
2010
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876953/ https://ncbi.nlm.nih.gov/pubmed/20407424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.49 |
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