TRF1 and TRF2 binding to telomeres is modulated by nucleosomal organization

The ends of eukaryotic chromosomes need to be protected from the activation of a DNA damage response that leads the cell to replicative senescence or apoptosis. In mammals, protection is accomplished by a six-factor complex named shelterin, which organizes the terminal TTAGGG repeats in a still ill-...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Galati, Alessandra, Micheli, Emanuela, Alicata, Claudia, Ingegnere, Tiziano, Cicconi, Alessandro, Pusch, Miriam Caroline, Giraud-Panis, Marie-Josèphe, Gilson, Eric, Cacchione, Stefano
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499135/
https://ncbi.nlm.nih.gov/pubmed/25999344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv507
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