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TRF1 and TRF2 binding to telomeres is modulated by nucleosomal organization
The ends of eukaryotic chromosomes need to be protected from the activation of a DNA damage response that leads the cell to replicative senescence or apoptosis. In mammals, protection is accomplished by a six-factor complex named shelterin, which organizes the terminal TTAGGG repeats in a still ill-...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499135/ https://ncbi.nlm.nih.gov/pubmed/25999344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv507 |
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