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TRF2 promotes, remodels and protects telomeric Holliday junctions
The ability of the telomeric DNA-binding protein, TRF2, to stimulate t-loop formation while preventing t-loop deletion is believed to be crucial to maintain telomere integrity in mammals. However, little is known on the molecular mechanisms behind these properties of TRF2. In this report, we show th...
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Main Authors: | , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666026/ https://ncbi.nlm.nih.gov/pubmed/19197240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.11 |
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