TRF2 promotes, remodels and protects telomeric Holliday junctions

The ability of the telomeric DNA-binding protein, TRF2, to stimulate t-loop formation while preventing t-loop deletion is believed to be crucial to maintain telomere integrity in mammals. However, little is known on the molecular mechanisms behind these properties of TRF2. In this report, we show th...

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Autori principali: Poulet, Anaïs, Buisson, Rémi, Faivre-Moskalenko, Cendrine, Koelblen, Mélanie, Amiard, Simon, Montel, Fabien, Cuesta-Lopez, Santiago, Bornet, Olivier, Guerlesquin, Françoise, Godet, Thomas, Moukhtar, Julien, Argoul, Françoise, Déclais, Anne-Cécile, Lilley, David M J, Ip, Stephen C Y, West, Stephen C, Gilson, Eric, Giraud-Panis, Marie-Josèphe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666026/
https://ncbi.nlm.nih.gov/pubmed/19197240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.11
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