TRF2 promotes, remodels and protects telomeric Holliday junctions

The ability of the telomeric DNA-binding protein, TRF2, to stimulate t-loop formation while preventing t-loop deletion is believed to be crucial to maintain telomere integrity in mammals. However, little is known on the molecular mechanisms behind these properties of TRF2. In this report, we show th...

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Main Authors: Poulet, Anaïs, Buisson, Rémi, Faivre-Moskalenko, Cendrine, Koelblen, Mélanie, Amiard, Simon, Montel, Fabien, Cuesta-Lopez, Santiago, Bornet, Olivier, Guerlesquin, Françoise, Godet, Thomas, Moukhtar, Julien, Argoul, Françoise, Déclais, Anne-Cécile, Lilley, David M J, Ip, Stephen C Y, West, Stephen C, Gilson, Eric, Giraud-Panis, Marie-Josèphe
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666026/
https://ncbi.nlm.nih.gov/pubmed/19197240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.11
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