The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA

TRF1 and TRF2 are key proteins in human telomeres, which, despite their similarities, have different behaviors upon DNA binding. Previous work has shown that unlike TRF1, TRF2 condenses telomeric, thus creating consequential negative torsion on the adjacent DNA, a property that is thought to lead to...

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Detalhes bibliográficos
Main Authors: Poulet, Anaïs, Pisano, Sabrina, Faivre-Moskalenko, Cendrine, Pei, Bei, Tauran, Yannick, Haftek-Terreau, Zofia, Brunet, Frédéric, Le Bihan, Yann-Vaï, Ledu, Marie-Hélène, Montel, Fabien, Hugo, Nicolas, Amiard, Simon, Argoul, Françoise, Chaboud, Annie, Gilson, Eric, Giraud-Panis, Marie-Josèphe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315331/
https://ncbi.nlm.nih.gov/pubmed/22139926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1116
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