The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA

TRF1 and TRF2 are key proteins in human telomeres, which, despite their similarities, have different behaviors upon DNA binding. Previous work has shown that unlike TRF1, TRF2 condenses telomeric, thus creating consequential negative torsion on the adjacent DNA, a property that is thought to lead to...

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Dettagli Bibliografici
Autori principali: Poulet, Anaïs, Pisano, Sabrina, Faivre-Moskalenko, Cendrine, Pei, Bei, Tauran, Yannick, Haftek-Terreau, Zofia, Brunet, Frédéric, Le Bihan, Yann-Vaï, Ledu, Marie-Hélène, Montel, Fabien, Hugo, Nicolas, Amiard, Simon, Argoul, Françoise, Chaboud, Annie, Gilson, Eric, Giraud-Panis, Marie-Josèphe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Molecular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315331/
https://ncbi.nlm.nih.gov/pubmed/22139926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1116
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