The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA

TRF1 and TRF2 are key proteins in human telomeres, which, despite their similarities, have different behaviors upon DNA binding. Previous work has shown that unlike TRF1, TRF2 condenses telomeric, thus creating consequential negative torsion on the adjacent DNA, a property that is thought to lead to...

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Bibliografiska uppgifter
Huvudupphovsmän: Poulet, Anaïs, Pisano, Sabrina, Faivre-Moskalenko, Cendrine, Pei, Bei, Tauran, Yannick, Haftek-Terreau, Zofia, Brunet, Frédéric, Le Bihan, Yann-Vaï, Ledu, Marie-Hélène, Montel, Fabien, Hugo, Nicolas, Amiard, Simon, Argoul, Françoise, Chaboud, Annie, Gilson, Eric, Giraud-Panis, Marie-Josèphe
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
Ämnen:
Molecular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315331/
https://ncbi.nlm.nih.gov/pubmed/22139926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1116
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