The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA

TRF1 and TRF2 are key proteins in human telomeres, which, despite their similarities, have different behaviors upon DNA binding. Previous work has shown that unlike TRF1, TRF2 condenses telomeric, thus creating consequential negative torsion on the adjacent DNA, a property that is thought to lead to...

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Detaylı Bibliyografya
Asıl Yazarlar: Poulet, Anaïs, Pisano, Sabrina, Faivre-Moskalenko, Cendrine, Pei, Bei, Tauran, Yannick, Haftek-Terreau, Zofia, Brunet, Frédéric, Le Bihan, Yann-Vaï, Ledu, Marie-Hélène, Montel, Fabien, Hugo, Nicolas, Amiard, Simon, Argoul, Françoise, Chaboud, Annie, Gilson, Eric, Giraud-Panis, Marie-Josèphe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Molecular Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315331/
https://ncbi.nlm.nih.gov/pubmed/22139926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1116
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