A higher-order entity formed by the flexible assembly of RAP1 with TRF2

Telomere integrity is essential to maintain genome stability, and telomeric dysfunctions are associated with cancer and aging pathologies. In human, the shelterin complex binds TTAGGG DNA repeats and provides capping to chromosome ends. Within shelterin, RAP1 is recruited through its interaction wit...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Gaullier, Guillaume, Miron, Simona, Pisano, Sabrina, Buisson, Rémi, Le Bihan, Yann-Vaï, Tellier-Lebègue, Carine, Messaoud, Wala, Roblin, Pierre, Guimarães, Beatriz G., Thai, Robert, Giraud-Panis, Marie-Josèphe, Gilson, Eric, Le Du, Marie-Hélène
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770236/
https://ncbi.nlm.nih.gov/pubmed/26748096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1531
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