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Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation

Macrophage activation/polarization to distinct functional states is critically supported by metabolic shifts. How polarizing signals coordinate metabolic and functional reprogramming, and the potential implications for control of macrophage activation, remains poorly understood. Here we show that IL...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:eLife
Main Authors: Covarrubias, Anthony J, Aksoylar, Halil Ibrahim, Yu, Jiujiu, Snyder, Nathaniel W, Worth, Andrew J, Iyer, Shankar S, Wang, Jiawei, Ben-Sahra, Issam, Byles, Vanessa, Polynne-Stapornkul, Tiffany, Espinosa, Erika C, Lamming, Dudley, Manning, Brendan D, Zhang, Yijing, Blair, Ian A, Horng, Tiffany
פורמט: Artigo
שפה:Inglês
יצא לאור: eLife Sciences Publications, Ltd 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769166/
https://ncbi.nlm.nih.gov/pubmed/26894960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11612
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