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mTORC1 signaling and the metabolic control of cell growth

mTOR [mechanistic target of rapamycin] is a serine/threonine protein kinase that, as part of mTORC1 (mTOR complex 1), acts as an important molecular connection between nutrient signals and the metabolic processes indispensable for cell growth. While there has been pronounced interest in the upstream...

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Detalhes bibliográficos
Publicado no:Curr Opin Cell Biol
Main Authors: Ben-Sahra, Issam, Manning, Brendan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545101/
https://ncbi.nlm.nih.gov/pubmed/28411448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2017.02.012
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