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mTORC1 signaling and the metabolic control of cell growth

mTOR [mechanistic target of rapamycin] is a serine/threonine protein kinase that, as part of mTORC1 (mTOR complex 1), acts as an important molecular connection between nutrient signals and the metabolic processes indispensable for cell growth. While there has been pronounced interest in the upstream...

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Bibliographic Details
Published in:Curr Opin Cell Biol
Main Authors: Ben-Sahra, Issam, Manning, Brendan D.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545101/
https://ncbi.nlm.nih.gov/pubmed/28411448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2017.02.012
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