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mTORC1 signaling and the metabolic control of cell growth

mTOR [mechanistic target of rapamycin] is a serine/threonine protein kinase that, as part of mTORC1 (mTOR complex 1), acts as an important molecular connection between nutrient signals and the metabolic processes indispensable for cell growth. While there has been pronounced interest in the upstream...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Curr Opin Cell Biol
Hauptverfasser: Ben-Sahra, Issam, Manning, Brendan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545101/
https://ncbi.nlm.nih.gov/pubmed/28411448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2017.02.012
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