Llwytho...

The mTORC1 signaling network senses changes in cellular purine nucleotide levels

mTORC1 integrates signals from growth factors and nutrients to control biosynthetic processes, including protein, lipid and nucleic acid synthesis. We find that the mTORC1 pathway is responsive to changes in purine nucleotides in a manner analogous to its sensing of amino acids. Depletion of cellula...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Hoxhaj, Gerta, Hughes-Hallett, James, Timson, Rebecca, Ilagan, Erika, Yuan, Min, Asara, John M., Ben-Sahra, Issam, Manning, Brendan D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689476/
https://ncbi.nlm.nih.gov/pubmed/29091770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.029
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