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mTORC1 signaling and the metabolic control of cell growth

mTOR [mechanistic target of rapamycin] is a serine/threonine protein kinase that, as part of mTORC1 (mTOR complex 1), acts as an important molecular connection between nutrient signals and the metabolic processes indispensable for cell growth. While there has been pronounced interest in the upstream...

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Détails bibliographiques
Publié dans:Curr Opin Cell Biol
Auteurs principaux: Ben-Sahra, Issam, Manning, Brendan D.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545101/
https://ncbi.nlm.nih.gov/pubmed/28411448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2017.02.012
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