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mTORC1 signaling and the metabolic control of cell growth

mTOR [mechanistic target of rapamycin] is a serine/threonine protein kinase that, as part of mTORC1 (mTOR complex 1), acts as an important molecular connection between nutrient signals and the metabolic processes indispensable for cell growth. While there has been pronounced interest in the upstream...

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Bibliografiske detaljer
Udgivet i:Curr Opin Cell Biol
Main Authors: Ben-Sahra, Issam, Manning, Brendan D.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545101/
https://ncbi.nlm.nih.gov/pubmed/28411448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2017.02.012
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