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Next Generation Strategies for Geroprotection via mTORC1 Inhibition
Inhibition of mTORC1 (mechanistic Target Of Rapamycin Complex 1) with the pharmaceutical rapamycin prolongs the lifespan and healthspan of model organisms including rodents, with evidence now emerging that rapamycin and its analogs may also have rejuvenative effects in dogs and humans. However, the...
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| Publié dans: | J Gerontol A Biol Sci Med Sci |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6909887/ https://ncbi.nlm.nih.gov/pubmed/30794726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz056 |
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