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Next Generation Strategies for Geroprotection via mTORC1 Inhibition

Inhibition of mTORC1 (mechanistic Target Of Rapamycin Complex 1) with the pharmaceutical rapamycin prolongs the lifespan and healthspan of model organisms including rodents, with evidence now emerging that rapamycin and its analogs may also have rejuvenative effects in dogs and humans. However, the...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Gerontol A Biol Sci Med Sci
Päätekijät: Dumas, Sabrina N, Lamming, Dudley W
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909887/
https://ncbi.nlm.nih.gov/pubmed/30794726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz056
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