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Next Generation Strategies for Geroprotection via mTORC1 Inhibition
Inhibition of mTORC1 (mechanistic Target Of Rapamycin Complex 1) with the pharmaceutical rapamycin prolongs the lifespan and healthspan of model organisms including rodents, with evidence now emerging that rapamycin and its analogs may also have rejuvenative effects in dogs and humans. However, the...
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| Yayımlandı: | J Gerontol A Biol Sci Med Sci |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6909887/ https://ncbi.nlm.nih.gov/pubmed/30794726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz056 |
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