Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation

Macrophage activation/polarization to distinct functional states is critically supported by metabolic shifts. How polarizing signals coordinate metabolic and functional reprogramming, and the potential implications for control of macrophage activation, remains poorly understood. Here we show that IL...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Covarrubias, Anthony J, Aksoylar, Halil Ibrahim, Yu, Jiujiu, Snyder, Nathaniel W, Worth, Andrew J, Iyer, Shankar S, Wang, Jiawei, Ben-Sahra, Issam, Byles, Vanessa, Polynne-Stapornkul, Tiffany, Espinosa, Erika C, Lamming, Dudley, Manning, Brendan D, Zhang, Yijing, Blair, Ian A, Horng, Tiffany
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2016
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769166/
https://ncbi.nlm.nih.gov/pubmed/26894960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11612
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