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Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion Channel
GLIC receptor is a bacterial pentameric ligand-gated ion channel whose action is inhibited by xenon. Xenon has been used in clinical practice as a potent gaseous anaesthetic for decades, but the molecular mechanism of interactions with its integral membrane receptor targets remains poorly understood...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4765991/ https://ncbi.nlm.nih.gov/pubmed/26910105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149795 |
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