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Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel
Pentameric ligand-gated ion channels (pLGICs) are allosteric receptors that mediate rapid electrochemical signal transduction in the animal nervous system through the opening of an ion pore upon binding of neurotransmitters. Orthologs have been found and characterized in prokaryotes and they display...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7306758/ https://ncbi.nlm.nih.gov/pubmed/32482881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922701117 |
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