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Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel

The pentameric ligand-gated ion channel (pLGIC) from Gloeobacter violaceus (GLIC) has provided insightful structure–function views on the permeation process and the allosteric regulation of the pLGICs family. However, GLIC is activated by pH instead of a neurotransmitter and a clear picture for the...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Hu, Haidai, Ataka, Kenichi, Menny, Anaïs, Fourati, Zaineb, Sauguet, Ludovic, Corringer, Pierre-Jean, Koehl, Patrice, Heberle, Joachim, Delarue, Marc
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310827/
https://ncbi.nlm.nih.gov/pubmed/30541892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813378116
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