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Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel

The pentameric ligand-gated ion channel (pLGIC) from Gloeobacter violaceus (GLIC) has provided insightful structure–function views on the permeation process and the allosteric regulation of the pLGICs family. However, GLIC is activated by pH instead of a neurotransmitter and a clear picture for the...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Hu, Haidai, Ataka, Kenichi, Menny, Anaïs, Fourati, Zaineb, Sauguet, Ludovic, Corringer, Pierre-Jean, Koehl, Patrice, Heberle, Joachim, Delarue, Marc
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310827/
https://ncbi.nlm.nih.gov/pubmed/30541892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813378116
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