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Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel
The pentameric ligand-gated ion channel (pLGIC) from Gloeobacter violaceus (GLIC) has provided insightful structure–function views on the permeation process and the allosteric regulation of the pLGICs family. However, GLIC is activated by pH instead of a neurotransmitter and a clear picture for the...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6310827/ https://ncbi.nlm.nih.gov/pubmed/30541892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813378116 |
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