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Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro.

Gerstmann-Sträussler-Scheinker disease (GSS) is a prion-related encephalopathy pathologically characterized by massive deposition of prion protein (PrP) amyloid in the central nervous system. The major component of amyloid fibrils isolated from patients of the Indiana kindred of GSS (GSS-Ik) is an 1...

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Main Authors: Tagliavini, F, Prelli, F, Verga, L, Giaccone, G, Sarma, R, Gorevic, P, Ghetti, B, Passerini, F, Ghibaudi, E, Forloni, G
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1993
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC47633/
https://ncbi.nlm.nih.gov/pubmed/8105481
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