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Neurotoxic and Gliotrophic Activity of a Synthetic Peptide Homologous to Gerstmann–Sträussler–Scheinker Disease Amyloid Protein
Amyloid fibrils in Gerstmann–Sträussler–Scheinker (GSS) disease are composed of a fragment of the prion protein (PrP), the N and C termini of which correspond to ragged residues 81–90 and 144–153. A synthetic peptide spanning the sequence 82–146 (PrP 82–146) polymerizes into protease-resistant fibri...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6673725/ https://ncbi.nlm.nih.gov/pubmed/17301166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5145-06.2007 |
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