Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58.

Gerstmann-Sträussler-Scheinker (GSS) disease is a familial neurological disorder pathologically characterized by amyloid deposition in the cerebrum and cerebellum. The GSS amyloid is immunoreactive to antisera raised against the hamster prion protein (PrP) 27-30. This is a proteinase K-resistant gly...

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Detalhes bibliográficos
Main Authors: Tagliavini, F, Prelli, F, Ghiso, J, Bugiani, O, Serban, D, Prusiner, S B, Farlow, M R, Ghetti, B, Frangione, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC452678/
https://ncbi.nlm.nih.gov/pubmed/1672107
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