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Detection and delineation of oral cancer with a PARP1 targeted optical imaging agent

Earlier and more accurate detection of oral squamous cell carcinoma (OSCC) is essential to improve the prognosis of patients and to reduce the morbidity of surgical therapy. Here, we demonstrate that the nuclear enzyme Poly(ADP-ribose)Polymerase 1 (PARP1) is a promising target for optical imaging of...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Kossatz, Susanne, Brand, Christian, Gutiontov, Stanley, Liu, Jonathan T. C., Lee, Nancy Y., Gönen, Mithat, Weber, Wolfgang A., Reiner, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761964/
https://ncbi.nlm.nih.gov/pubmed/26900125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21371
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