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Optical Imaging of PARP1 in Response to Radiation in Oral Squamous Cell Carcinoma

Targeting and inhibiting DNA repair pathways is a powerful strategy of controlling malignant growth. One such strategy includes the inhibition of PARP1, a central element in the intracellular DNA damage response. To determine and visualize the expression and intercellular distribution of PARP1 in vi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kossatz, Susanne, Weber, Wolfgang A., Reiner, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726809/
https://ncbi.nlm.nih.gov/pubmed/26808835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147752
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