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Detection and delineation of oral cancer with a PARP1 targeted optical imaging agent

Earlier and more accurate detection of oral squamous cell carcinoma (OSCC) is essential to improve the prognosis of patients and to reduce the morbidity of surgical therapy. Here, we demonstrate that the nuclear enzyme Poly(ADP-ribose)Polymerase 1 (PARP1) is a promising target for optical imaging of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kossatz, Susanne, Brand, Christian, Gutiontov, Stanley, Liu, Jonathan T. C., Lee, Nancy Y., Gönen, Mithat, Weber, Wolfgang A., Reiner, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761964/
https://ncbi.nlm.nih.gov/pubmed/26900125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21371
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