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Detection and delineation of oral cancer with a PARP1 targeted optical imaging agent

Earlier and more accurate detection of oral squamous cell carcinoma (OSCC) is essential to improve the prognosis of patients and to reduce the morbidity of surgical therapy. Here, we demonstrate that the nuclear enzyme Poly(ADP-ribose)Polymerase 1 (PARP1) is a promising target for optical imaging of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Kossatz, Susanne, Brand, Christian, Gutiontov, Stanley, Liu, Jonathan T. C., Lee, Nancy Y., Gönen, Mithat, Weber, Wolfgang A., Reiner, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761964/
https://ncbi.nlm.nih.gov/pubmed/26900125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21371
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