Detection and delineation of oral cancer with a PARP1 targeted optical imaging agent

Earlier and more accurate detection of oral squamous cell carcinoma (OSCC) is essential to improve the prognosis of patients and to reduce the morbidity of surgical therapy. Here, we demonstrate that the nuclear enzyme Poly(ADP-ribose)Polymerase 1 (PARP1) is a promising target for optical imaging of...

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Foilsithe in:Sci Rep
Main Authors: Kossatz, Susanne, Brand, Christian, Gutiontov, Stanley, Liu, Jonathan T. C., Lee, Nancy Y., Gönen, Mithat, Weber, Wolfgang A., Reiner, Thomas
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761964/
https://ncbi.nlm.nih.gov/pubmed/26900125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21371
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