Mutational strand asymmetries in cancer genomes reveal mechanisms of DNA damage and repair

Mutational processes constantly shape the somatic genome, leading to immunity, aging, and other diseases. When cancer is the outcome, we are afforded a glimpse into these processes by the clonal expansion of the malignant cell. Here, we characterize a less explored layer of the mutational landscape...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell
Autors principals: Haradhvala, Nicholas J., Polak, Paz, Stojanov, Petar, Covington, Kyle R., Shinbrot, Eve, Hess, Julian, Rheinbay, Esther, Kim, Jaegil, Maruvka, Yosef, Braunstein, Lior Z., Kamburov, Atanas, Hanawalt, Philip C., Wheeler, David A., Koren, Amnon, Lawrence, Michael S., Getz, Gad
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753048/
https://ncbi.nlm.nih.gov/pubmed/26806129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.12.050
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars