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Somatic ERCC2 Mutations Are Associated with a Distinct Genomic Signature in Urothelial Tumors
Alterations in DNA repair pathways are common in tumors and can result in characteristic mutational signatures; however, a specific mutational signature associated with somatic alterations in the nucleotide excision repair (NER) pathway has not yet been identified. Here, we examine the mutational pr...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4936490/ https://ncbi.nlm.nih.gov/pubmed/27111033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3557 |
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