Mutational strand asymmetries in cancer genomes reveal mechanisms of DNA damage and repair

Mutational processes constantly shape the somatic genome, leading to immunity, aging, and other diseases. When cancer is the outcome, we are afforded a glimpse into these processes by the clonal expansion of the malignant cell. Here, we characterize a less explored layer of the mutational landscape...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Haradhvala, Nicholas J., Polak, Paz, Stojanov, Petar, Covington, Kyle R., Shinbrot, Eve, Hess, Julian, Rheinbay, Esther, Kim, Jaegil, Maruvka, Yosef, Braunstein, Lior Z., Kamburov, Atanas, Hanawalt, Philip C., Wheeler, David A., Koren, Amnon, Lawrence, Michael S., Getz, Gad
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753048/
https://ncbi.nlm.nih.gov/pubmed/26806129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.12.050
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