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Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy

Impaired autophagy has been implicated in many neurodegenerative diseases, such as Parkinson's disease (PD), and might be responsible for deposition of aggregated proteins in neurons. However, little is known how neuronal autophagy and clearance of aggregated proteins are regulated. Here, we sh...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Kim, Changyoun, Rockenstein, Edward, Spencer, Brian, Kim, Hyung-Koo, Adame, Anthony, Trejo, Margarita, Stafa, Klodjan, Lee, He-Jin, Lee, Seung-Jae, Masliah, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752835/
https://ncbi.nlm.nih.gov/pubmed/26489461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.044
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