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Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy

Impaired autophagy has been implicated in many neurodegenerative diseases, such as Parkinson's disease (PD), and might be responsible for deposition of aggregated proteins in neurons. However, little is known how neuronal autophagy and clearance of aggregated proteins are regulated. Here, we sh...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Kim, Changyoun, Rockenstein, Edward, Spencer, Brian, Kim, Hyung-Koo, Adame, Anthony, Trejo, Margarita, Stafa, Klodjan, Lee, He-Jin, Lee, Seung-Jae, Masliah, Eliezer
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752835/
https://ncbi.nlm.nih.gov/pubmed/26489461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.044
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